Genetic Tests

Genetic Tests

As a CLIA and CAP accredited clinical laboratory based in San Diego, California, Pathway Genomics provides physicians and their patients with actionable and accurate genetic information to improve or maintain health and wellness. Since its founding in 2008, Pathway Genomics has become known for its dedication to innovation and commitment to medical responsibility – making it a leader in the commercial genetic testing industry. Pathway Genomics’ testing services cover a variety of conditions including cardiac health, cancer risk, inherited diseases, nutrition and exercise response, as well as drug response for specific medications including those used in pain management and mental health. For more about Pathway Genomics, visit

Here are the tests we offer

Pathway Fit®

The Pathway Fit® nutrigenomic profile provides you with an individualized report with powerful information to help you understand how your genetics and lifestyle may affect your diet, nutrition and exercise. The report is like no other. It’s designed for your body, about your body. With your genetic information, you are able to gain insights into how your body may process sugars, fats, nutrients and vitamins. You can also learn how your genes might affect how you perceive and desire specific foods, and how they may influence eating behaviors. What’s more, Pathway Fit screens for muscle potential and how your body responds to exercise, as well as your potential to maintain a healthy weight. Start living smarter, not harder with these key findings. Pathway Fit, your genetic fitness profile.

Pathway Fit® may help with:


  • Weight management.
  • Increased mental and physical performance.
  • Maximizing energy.
  • Disease prevention.


Healthy Weight DNA Insight™

Clinical studies have shown that individuals who follow a genetically appropriate diet lose weight more easily. With Healthy Woman DNA Insight™, patients will have a holistic view of their health and may finally be able to achieve a more desirable weight, manage potential health conditions, as well as have powerful information as to which medications may or may not be right for them.

Based on a saliva sample, Healthy Woman DNA Insight tests a variety of genes that influence response to diet, metabolism, and exercise, as well as the propensity to develop certain health conditions and likely response to specific medications.


  • May help to better manage postpartum weight loss.
  • Aids in identifying behaviors that may need to be managed.
  • Provides information to promote improvement in overall health and wellness.


Cardiac DNA Insight®

Cardiac DNA Insight® can help identify a patient’s propensity for increased risk of certain heart-related health conditions. This report also examines eight classes of drugs that affect the cardiovascular system: anti-platelets, anti-coagulants, statins, stimulants, beta-blockers, ACE inhibitors, calcium channel blockers and hormone therapies. Cardiac DNA Insight may be used to enhance the information provided in lipid tests that evaluate risk for cardiovascular disease.


  • Better monitor a patient’s specific health condition.
  • Prescribe a more optimal medication and dosage for a patient.
  • Suggest early lifestyle and diet interventions to help combat or prevent certain health conditions.


Cardiac Healthy Weight DNA Insight®

With just a simple saliva sample, Cardiac Healthy Weight DNA Insight® can help physicians and patients understand how genetics and lifestyle affect diet, nutrition, weight and overall heart health. Clinical studies have shown that individuals who follow a genetically appropriate diet lose significantly more weight and are able to maintain weight loss more easily than those on a diet not based on their genetics.


  • Provides specific genetic information including matching diet type, nutritional needs and genetic propensities.
  • May help reduce the risk of heart disease by making appropriate diet and nutritional changes.
  • Provides personalized approach to healthy weight loss.


Carrier Status DNA Insight®

Pathway Genomics’ carrier status test provides relevant genetic insights to inform physicians about the health of their patients’ future children. By following the American College of Obstetricians and Gynecologists (ACOG) recommendations, we offer a comprehensive preconception and prenatal carrier screening test.

Not all tests are created equal.

Carrier Status DNA Insight® offers more ACOG-recommended conditions than most other carrier tests on the market today, providing physicians with powerful carrier-associated information from a single source.


  • Screens patients for more than 70 recessive genetic diseases.
  • Supported by rigorous science using clinically-relevant, well-validated markers and assays.
  • Requires only a non-invasive saliva sample for most conditions.
  • Enables physicians to offer calculated guidance on pre- and postnatal health.


Mental Health DNA Insight™

Mental Health DNA Insight™ analyzes a patient’s DNA to identify genetic variants that affect the metabolism and efficacy of psychiatric medications. Genetic research suggests that categorizing individuals based on genotypes will make the pharmacologic treatment of psychiatric illnesses more predictable and effective. Mental Health DNA Insight can help a physician predict a patient’s response to more than 40 common antidepressants, mood stabilizers and anti psychotic medications. The report provides outcomes in a clear color-coded chart.


  • Green: prescribe the drug as directed in the product insert.
  • Orange: caution. For medications in this category, the outcome may indicate that dosing levels need to be lowered or increased, or that the drug’s side effects may cause an adverse reaction for this patient.
  • Red: use with caution and with more frequent monitoring, due to risk of severe adverse reaction or lack of therapeutic response. Alternative medications are strongly recommended.


Pain Medication DNA Insight™

Pain Medication DNA Insight™ identifies genetic variants that affect how an individual will respond to the analgesic effects of certain types of commonly prescribed pain medications. This clinically actionable genetic test can assist the physician in identifying each patient’s optimal treatment plan.


  • Prescribe a more appropriate medication and optimal dosage for a patient.
  • Avoid potentially severe and life-threatening side effects or a lack of drug efficacy.
  • Avoid the misinterpretation of drug-seeking behavior.



SkinFit™ tests for genetic predispositions to skin aging, sun sensitivity, development of dry skin and wrinkles, skin allergy risk, elasticity, and skin texture. The test also analyzes genetic markers associated with micro nutrient deficiencies.



Understanding what genetic risk factors a patient possesses can help create personalized risk-reducing strategies and guide preventive measures.

Pathway Genomics can help to understand a patient’s cancer risk, facilitate genetic and medical counseling, as well as assist physicians in making informed health care decisions

Patient Target Criteria for Testing


  • Early onset colorectal cancer.
  • History of adenomas under the age of 50.
  • Large clusters of adenomas (>10) at any age.
  • History of ovarian, uterine, or other cancers in first or second-degree relatives. Benefits of Testing
  • Modifying frequency and age of onset for targeted cancer screening.
  • Determining targeted risk reduction or preventive strategies.
  • Identifying if additional family members may be at risk.


Familial Studies Program
Based on a simple saliva sample, Pathway Genomics’ ColoTrueTM uses next-generation sequencing (NGS) technology to identify genetic changes that increase a patient’s risk of developing certain types of cancer.

In the process of sequencing the patient’s DNA, we may identify a genetic change with no clear cancer association, or a change in which conflicting data exist. These genetic changes are called variants of unknown significance (VUS). Pathway Genomics offers a complimentary Familial Studies Program to help understand the significance of these genetic changes, and how the patient and family members may be affected.